Total synthesis of Taxol. 4. The final stages and completion of the synthesis

DOI: 10.1021/ja00107a009

Source and publish data:

Journal of the American Chemical Society p. 653 - 659 (1995)

Update date:2022-08-04

Topics:

Authors:

Nicolaou

Ueno Ueno

Liu Liu

Nantermet

Yang Yang

Renaud Renaud

Paulvannan

Chadha Chadha

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00107a009

The total synthesis of (-)-Taxol has been achieved. Functional group manipulation of diol 2 provided the ABC ring system with the correct C9-keto, C10-acetyloxy functionality. Careful optimization allowed the oxidation of the C5-C6 alkene in 4 at C5 via a

Full text of DOI:10.1021/ja00107a009

Products guided by the article

Product name:C₃₃H₄₂O₉

Cas No:162088-37-1

R&D Labs maybe for 162088-37-1

Changzhou Ruiping Chemical Co., Ltd

website:http://www.wishchem.com

Contact:+86-519-82324280

Address:No.288-1 Huacheng Road, Jintan
WD Silicone Co., Ltd

Contact:+86-27-87204219, +86-27-87215023

Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
MiHecb Bio-Tech Co., Ltd.

Contact:+86-0592 5353131

Address:No.56 Guani Road Software Park 2,Siming District
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Hangzhou Chemfar Ltd.

Contact:+86-571-87859231, 87859237, 87859239

Address:1606,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China, 310053

Relevant to this article

Synthesis of a new type of conformationally constrained α,α-disubstituted-β-amino acids and β-lactams in enantiomerically pure form

Doi:10.1016/0957-4166(95)00174-N
(1995)
ONE-STEP SYNTHESIS OF 2-AMINO-3-FURANCARBOXYLIC ACID DERIVATIVES FROM 2-FURANCARBALDEHYDE

Doi:10.1135/cccc19942481
(1994)
Successive reactions of rhenium isocyanide complexes with nitrogen-containing ligands. One-flask conversion of ReBr(CO)₄(CNPh) to [Re(CO)₃(NH₂R)₂{C(NHPh)(NHR)}] ⁺Br^-

Doi:10.1021/om00002a045
(1995)
Solid-phase synthesis of cyclic lipopeptidotriazoles

Doi:10.1002/ejoc.201402111
(2014)
Synthesis and Evaluation of Compounds That Affect Soybean Cyst Nematode Egg Hatch

Doi:10.1021/jf00045a001
(1994)
Biodegradable microspheres. 17. Lysosomal degradation of primaquine- peptide spacer arms

Doi:10.1002/jps.2600840227
(1995)

Article Doi