Tetrahedron Letters p. 1035 - 1038 (1995)
Update date:2022-08-02
Topics: Optimization Cyclization Purification and Isolation Analysis and Characterization
Varea, Teresa
Dufour, Monique
Micouin, Laurent
Riche, Claude
Chiaroni, Angele
Quirion, Jean-Charles
Husson, Henri-Philippe
A series of 2-methyl-5-substituted piperidines in enantiomerically pure form has been synthesized from lactam 3a. The stereospecific alkylation involved a rigid amide enolate.
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