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Synthesis of some retinoids bearing different heterocyclic rings with anticancer activity

DOI: 10.1016/0223-5234(94)90136-8

Source and publish data:

European Journal of Medicinal Chemistry p. 773 - 780 (1994)

Update date:2022-08-03

Topics:

Authors:

Barrero, A. F.Barrero, A. F.

Sanchez, J. F.Sanchez, J. F.

Oltra, J. E.Oltra, J. E.

Teva, D.Teva, D.

Ferrol, R. R.Ferrol, R. R.

et al.et al.

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Article abstract of DOI:10.1016/0223-5234(94)90136-8

The synthesis of a series of pyrrole and imidazole retinoids is reported.The compounds were obtained by means of reactions of phosphoranes or phosphonates with aldehydes.Several of these retinoids were evaluated against different tumor systems and some we

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Full text of DOI:10.1016/0223-5234(94)90136-8

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Product name:(2E,4E)-3-Methyl-5-(1-p-tolyl-1H-imidazol-4-yl)-penta-2,4-dienoic acid methyl ester

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