Tetrahedron Letters p. 7193 - 7196 (1994)
Update date:2022-08-03
Topics:
Vinod, Thottumkara K.
The synthesis of the isosteric phosphonate substrate analogue inhibitor 2 and the isopolar difluoromethylenephosphonate inhibitor 3 for phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus cereus is described. The key step involved a trichloroacetonitrile mediated condensation between the inositol derivative 8 and the corresponding phosphonic acids 16 and 18 to establish the central P-O bond in these inhibitors.
View MoreZibo Ocean International Trade Co.,Ltd(expird)
Contact:+86 533 5160706
Address:1117, Hongtai Bld., Songling rd, Zichuan,Zibo,Shandong,China
Shanghai birch chemical technology co.,ltd
Contact:+86-21-54096810
Address:No.2588,Jungong Road,Shanghai,China
Contact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Contact:0510-85393305
Address:1619 Huishan Avenue, Huishan District, Wuxi,
Sinoway International (Jiangsu) Co., Ltd.
Contact:+86-25-86630167
Address:17 Beijing Road (West), Nanjing, China
Doi:10.1021/acs.orglett.6b01091
(2016)Doi:10.1002/ejic.201402123
(2014)Doi:10.1021/ja01270a050
(1938)Doi:10.1016/j.tetlet.2013.06.060
(2013)Doi:10.1016/j.tetlet.2016.12.056
(2017)Doi:10.1002/adsc.201300945
(2014)
