Steroid complexation by cyclophane receptors in aqueous solution: Substrate selectivity, enthalpic driving force for cavity inclusion, and enthalpy-entropy compensation

Article abstract of DOI:10.1016/0040-4020(94)00905-A

The synthesis, characterization, and steroid binding properties of two novel cyclophane receptors shaped by two naphthylphenylmethane spacers are reported. Cyclophane 1 forms inclusion complexes with bile acids, corticoids, and androgenic steroids in D