Neuromediator analogs: Synthesis of cis (2R,3S) and trans (2S,3S)-2,3-piperidine dicarboxylic acids from (2S)-2-phenylglycinol

DOI: 10.1016/0040-4039(95)00088-T

Source and publish data:

Tetrahedron Letters p. 1657 - 1660 (1995)

Update date:2022-08-03

Topics:

Authors:

Agami, Claude

Kadouri-Puchot, Catherine

Le Guen, Valerie

Vaissermann, Jacqueline

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Article abstract of DOI:10.1016/0040-4039(95)00088-T

The cis and trans isomers of 2,3-piperidine dicarboxylic acids were obtained in enantiopure forms from the same chiral inductor: 2-phenylglycinol. This synthesis was mainly based on a δ-lactam formation via Stille's aza-annulation/hydrogenation procedure

Full text of DOI:10.1016/0040-4039(95)00088-T

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