Chemical and Pharmaceutical Bulletin p. 2254 - 2258 (1996)
Update date:2022-08-05
Topics:
Saeki, Ken-Ichi
Tomomitsu, Masato
Kawazoe, Yutaka
Momota, Kunitaka
Kimoto, Hiroshi
Thirteen kinds of fluorinated derivatives of benzo[h]quinoline and benzo[f]qninoline were synthesized by means of the Schiemann reaction or Skraup reaction, or by an electrolytic method. The synthesized derivatives carry one or two fluorine atoms at the bay-region, the K-region, and/or on the pyridine moiety of the molecules. These compounds can be used as models to examine the effect upon genotoxicity of fluorine substitution at appropriate sites on aromatic rings. Physicochemical and spectroscopic data of the fluorinated derivatives are given.
View MoreTaizhou Chemedir Biopharm-tech Co., Ltd
Contact:+86 523 86200218
Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China
Jinan Decheng Hemu Medical Technology Co.,Ltd.
Contact:+86-531-68650525
Address:NO.554 Zhengfeng Road High-new Technology Development Zone
Chengdu Baishixing Science and Technology Industry Co., Ltd.
website:http://www.cd-bsx.com
Contact:+86-28-88531548
Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
Shangyu Sanhechemicals Co.,LTD.
Contact:86-0571-56696839
Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
website:http://www.shochem.com
Contact:021-50800795
Address:No.1043, Halei Rd, Zhangjiang Hi-Tech Park, Shanghai, Postcode 201203, China
Doi:10.1021/acs.jmedchem.8b00029
(2018)Doi:10.1134/S1070363211060144
(2011)Doi:10.1021/jm00007a005
(1995)Doi:10.1002/adsc.201400057
(2014)Doi:10.1002/cctc.202000070
(2020)Doi:10.1021/jo00107a007
(1995)