Determination of the absolute configurations and total synthesis of new immunosuppressants, mycestericins E and G

Article abstract of DOI:10.1016/0040-4039(95)01823-Z

The absolute configurations of two new immunosuppressant, mycestericins E (1) and G (2), were established and both compounds were synthesized starting from 1,8-octanediol and a fully protected methyl (2S,4R)-oxazolidine-4-carboxylate 3. Compounds 5 and 22