Synthesis of Novel α-(Acyloxy)-α-(quinolin-4-yl)acetamides by a Three-Component Reaction between an Isocyanide, Quinoline-4-carbaldehyde, and Arenecarboxylic Acids

Article abstract of DOI:10.1002/hlca.201300378

Novel α-(acyloxy)-α-(quinolin-4-yl)acetamides were synthesized by the Passerini three-component reaction between an isocyanide, quinoline-4-carbaldehyde, and arenecarboxylic acids in H₂O. The reactions were carried out in one pot at room temperature with quantitative yields. Copyright