TABLE 2. 1H NMR Spectra of the Isoxazolines 12-19
Com-
pound
Chemical shifts, δ, ppm (SSCC, J, Hz)
12
3.56 (1H, dd, J = 8.3, J = 17.1, CH); 3.60 (1H, dd, J = 9.3, J = 17.1, CH);
4.17 (1H, dd, J = 5.1, J = 10.0, CH); 4.21 (1H, dd, J = 4.4, J = 10.0, CH);
5.05-5.21 (1Н, m, СН); 6.84 (1Н, d, J = 8.8, Нarom.); 7.37 (1H, dd, J = 2.4, J = 8.8, Нarom.);
7.42-7.47 (3Н, m, Нarom.); 7.68 (1Н, d, J = 2.4, Нarom.); 7.74-7.80 (2Н, m, Нarom.
)
13
3.28 (1H, dd, J = 7.4, J = 15.2, CH); 3.49 (1H, dd, J = 9.2, J = 15.2, CH);
4.01(1H, dd, J = 5.6, J = 10.1, CH); 4.16 (1H, dd, J = 4.2, J = 10.1, CH);
4.94-5.25 (1Н, m, СН); 6.81 (2Н, d, J = 8.6, Нarom.); 7.18 (2Н, d, J = 8.6, Нarom.);
7.52 (4Н, s, Нarom.
)
14
15
2.03 (3H, s, CH3); 3.32 (1H, dd, J = 7.4, J = 16.6, CH); 3.52 (1H, dd, J = 9.2, J = 16.6, CH);
4.03 (2H, m, CH2); 4.96-5.27 (1Н, m, СН); 6.69 (1Н, d, J = 8.8, Нarom.);
6.98-7.14 (2Н, m, Нarom.); 7.36 (2Н, d, J = 8.4, Нarom.); 7.61 (2Н, d, J = 8.4, Нarom.
)
3.51 (1H, dd, J = 7.3, J = 17.0, CH); 3.61 (1H, dd, J = 10.2, J = 17.0, CH);
4.16 (1H, dd, J = 5.1, J = 9.9, CH); 4.22 (1H, dd, J = 4.2, J = 9.9, CH);
5.02-5.21 (1Н, m, СН); 7.08 (1Н, s, Нarom.); 7.45-7.47 (4Н, m, Нarom.);
7.72-7.77 (2Н, m, Нarom.
)
16
17
3.43 (1H, dd, J = 9.8, J = 16.3, CH); 3.58 (1H, dd, J = 10.3, J = 16.3, CH);
4.09 (1H, dd, J = 5.9, J = 9.9, CH); 4.21 (1H, dd, J = 4.8, J = 9.9, CH);
4.55-5.29 (1Н, m, СН); 7.25 (2Н, s, Нarom.); 7.52 (4Н, s, Нarom.
)
3.32 (1H, dd, J = 7.2, J = 14.2, CH); 3.58 (1H, dd, J = 9.6, J = 14.2, CH);
4.14 (1H, dd, J = 5.2, J = 8.4, CH); 4.25 (1H, dd, J = 4.2, J = 8.4, CH);
4.98-5.29 (1Н, m, СН); 6.94 (2Н, d, J = 9.2, Нarom.); 7.32-7.45 (3Н, m, Нarom.);
7.54-7.69 (2Н, m, Нarom.); 8.14 (2Н, d, J = 9.2, Нarom.
)
18
19
1.34 (3H, t, J = 7.0, CH3); 3.29 (1H, dd, J = 7.6, J = 15.4, CH); 3.49 (1H, dd, J = 9.4,
J = 15.4, CH); 4.07 (1H, dd, J = 5.8, J = 9.2, CH); 4.21 (1H, dd, J = 4.4, J = 9.2, CH);
4.32 (2H, q, J = 7.0, CH2); 4.96-5.27 (1Н, m, СН); 6.85 (2Н, d, J = 8.0, Нarom.);
7.34 (2Н, d, J = 8.4, Нarom.); 7.58 (2Н, d, J = 8.4, Нarom.); 7.94 (2Н, d, J = 8.0, Нarom.
)
3.12 (1H, dd, J = 7.2, J = 16.3, CH); 3.18 (1H, dd, J = 8.2, J = 16.8, CH);
3.43 (1H, dd, J = 10.3, J =16.3, CH); 3.49 (1H, dd, J = 13.5, J = 16.8, CH);
4.12-4.16 (2Н, m, СН2); 4.29-4.36 (2Н, m, CН2); 4.81-5.29 (2Н, m, 2×CН);
6.94 (1Н, d, J = 8.6, Нarom.); 7.32-7.40 (6Н, m, Нarom.); 7.58-7.72 (6Н, m, Нarom.
)
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