Journal of Medicinal Chemistry p. 2041 - 2049 (1995)
Update date:2022-07-30
Topics:
Cushman
He
Katzenellenbogen
Lin
Hamel
In order to define the structural parameters associated with the antitubulin activity and cytotoxicity of 2-methoxyestradiol, a mammalian metabolite of estradiol, an array of analogs was synthesized and evaluated. The potencies of the new congeners as inh
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