Thieno[2,3-d]pyrimidine-3-acetic acids a new class of nonpeptide endothelin receptor antagonists

DOI: 10.1248/cpb.46.1724

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1724 - 1737 (1998)

Update date:2022-08-03

Topics:

Authors:

Cho, Nobuo

Nara, Yoshi

Harada, Mioko

Sugo, Tsukasa

Masuda, Yasushi

Abe, Akemi

Kusumoto, Keiji

Itoh, Yasuaki

Ohtaki, Tetsuya

Watanabe, Toshifumi

Furuya, Shuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.1724

On the basis of structural information for the cyclic hexapeptide endothelin (ET) receptor antagonist, TAK-044, a series of thieno[2,3- d]pyrimidine-2,4-dione derivatives bearing a carboxyl group and aromatic rings that were important for receptor binding

Full text of DOI:10.1248/cpb.46.1724

NII-Electronic Library Service

Products guided by the article

Product name:ethyl 6-(4-methoxyphenyl)-5-methyl-1-(2-methylaminobenzyl)-2,4-dioxo-1,2,3,4-tetrahydrothienol<2,3-d>pyrimidine-3-acetate

Cas No:165809-19-8

R&D Labs maybe for 165809-19-8

Zhejiang Haizhou Pharmaceutical Co., Ltd.

website:https://www.haizhoupharma.com/

Contact:+86-576-88221016

Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
LianYunGang Chiral Chemical(CHINA) CO.,LTD

Contact:+86-518-83616958 +86-519-82884848

Address:LianYunGang Chemical Industry Park (JiangSu)
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Changyi Xinxing Technology Development Co., Ltd.

Contact:0086-510-86651065(Time Zone:8),86651656

Address:94 Yingbinxilu WestRoad, Huangtu Town, Jiangyin City, Jiangsu, China
SPRING CHEMICAL INDUSTRY CO.,LTD

Contact:86-187-66672125

Address:linchi industry park.zouping

Relevant to this article

A fluorous capping strategy for Fmoc-based automated and manual solid-phase peptide synthesis

Doi:10.1002/ejoc.200500958
(2006)
Hypercoordinafion of boron and aluminum: Synthetic utility as chelating lewis acids [7]

Doi:10.1021/ja9736828
(1998)
Palladium-Catalyzed Reductive Homocoupling Reaction of 3-Silylpropargyl Carbonates. New Entry into Allene-Yne Compounds

Doi:10.1021/jo00119a052
(1995)
Synthesis of cyclic acylated enamino esters from enol lactones, 4-keto amides, and 5-hydroxy lactams

Doi:10.1021/jo00110a026
(1995)
Synthesis of Novel 5-Hydroxy-3-alkoxy- And 5-Hydroxy-3-alkylthio-indole-2-carboxamides

Doi:10.1002/jhet.5570330614
(1996)
Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents

Doi:10.1016/j.bmc.2010.06.033
(2010)

Article Doi