Tetrahydrothienopyridine derivatives as novel GPIIB/IIIA antagonists

DOI: 10.1016/0960-894X(96)00476-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2601 - 2606 (1996)

Update date:2022-07-29

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Authors:

Katano, Kiyoaki

Shitara, Eiki

Shimizu, Masaro

Sasaki, Kazue

Miura, Tomoaki

Isomura, Yasuko

Kawaguchi, Mami

Ohuchi, Shokichi

Tsuruoka, Takashi

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Article abstract of DOI:10.1016/0960-894X(96)00476-3

The tetrahydrothienopyridine derivatives were derived from aminomethylcyclohexylcarboxylic acid as a lead moiety. Evaluation of the antiplatelet activity and receptor binding assay revealed that compound 1 (Me3277) was a novel and potent non-peptide and n

Full text of DOI:10.1016/0960-894X(96)00476-3

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