Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies

DOI: 10.1021/jm00014a021

Source and publish data:

Journal of Medicinal Chemistry p. 2692 - 2704 (1995)

Update date:2022-08-04

Topics:

Authors:

Anzini, Maurizio

Cappelli, Andrea

Vomero, Salvatore

Giorgi, Gianluca

Langer, Thierry

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00014a021

Synthesis and pharmacological evaluation of a series of condensed quinoline derivatives bearing a basic nitrogen on piperazine or <(dimethylamino)ethyl>thio moieties attached at the 2-position of the quinoline nucleus are described. 5-HT receptor binding

Full text of DOI:10.1021/jm00014a021

Products guided by the article

Product name:2-chloro-2'-(2-fluorobenzoyl)acetanilide

Cas No:165966-25-6

R&D Labs maybe for 165966-25-6

Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China
HUNAN OUYA BIOLOGICAL CO.,LTD

Contact:+8613400661290

Address:No 908,Kangwan Rd, Liuyang Economic
Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
HAORUI ENTERPRISES LLC

Contact:(1) 206-3550089

Address:5115 NE 8TH PL, Renton, WA 98059 USA

Relevant to this article

Total synthesis of the bicyclic depsipeptide hdac inhibitors spiruchostatins a and b, 5″-epi-spiruchostatin b, fk228 (fr901228) and preliminary evaluation of their biological activity

Doi:10.1002/chem.200901552
(2009)
Synthesis and catalytic properties of novel ruthenium N-heterocyclic-carbene complexes

Doi:10.1016/j.jorganchem.2009.08.030
(2009)
Bimetallic Catalytic Asymmetric Tandem Reaction of β-Alkynyl Ketones to Synthesize 6,6-Spiroketals

Doi:10.1002/anie.201812842
(2019)
Synthesis and evaluation of pyrrolin-2-one compounds, a series of plasminogen activator inhibitor-1 inhibitors

Doi:10.1248/cpb.57.979
(2009)
Conformationally Constrained Peptides. Chirospecific Synthesis of 4-Alkyl-Substituted γ-Lactam-Bridged Dipeptides from L-Aspartic Acid

Doi:10.1021/jo00274a037
(1989)
Synthesis and insecticidal activity of N - Tert -Butyl- N, N ′-diacylhydrazines containing 1,2,3-thiadiazoles

Doi:10.1021/jf104004q
(2011)

Article Doi