Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies

DOI: 10.1021/jm00014a021

Source and publish data:

Journal of Medicinal Chemistry p. 2692 - 2704 (1995)

Update date:2022-08-04

Topics:

Authors:

Anzini, Maurizio

Cappelli, Andrea

Vomero, Salvatore

Giorgi, Gianluca

Langer, Thierry

et al. et al.

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Article abstract of DOI:10.1021/jm00014a021

Synthesis and pharmacological evaluation of a series of condensed quinoline derivatives bearing a basic nitrogen on piperazine or <(dimethylamino)ethyl>thio moieties attached at the 2-position of the quinoline nucleus are described. 5-HT receptor binding

Full text of DOI:10.1021/jm00014a021

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