Studies on pyridonecarboxylic acids. III. Synthesis and antibacterial activity evaluation of 1,8-disubstituted 6-fluoro-4-oxo-7-piperazinyl-4H-[1,3]thiazeto[3,2-a] quinoline-3-carboxylic acid derivatives

DOI: 10.1248/cpb.43.63

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 63 - 70 (1995)

Update date:2022-08-02

Topics:

Authors:

Segawa Segawa

Kazuno Kazuno

Matsuoka

Shirahase

Ozaki Ozaki

Matsuda Matsuda

Tomii Tomii

Kitano Kitano

Kise Kise

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.43.63

A series of 1,8-disubstituted 6-fluoro-4-oxo-7-piperazinyl-4H-[1,3]thiazeto[3,2-a] quinoline-3-carboxylic acid derivatives was prepared and evaluated for antibacterial activity. In the 7-piperazinyl series, addition of a fluorine at C-8, which increased t

Full text of DOI:10.1248/cpb.43.63

NII-Electronic Library Service

Products guided by the article

Product name:6,7,8-Trifluoro-1-(4-fluoro-phenyl)-4-oxo-4H-2-thia-8b-aza-cyclobuta[a]naphthalene-3-carboxylic acid ethyl ester

Cas No:166042-40-6

R&D Labs maybe for 166042-40-6

Suzhou Howsine Biological Technology Co.,Ltd(expird)

website:http://www.howsine.com

Contact:86-512-67262751

Address:No 3,Weihua Road ,Suzhou Industrial Park ,Jiangsu ,China.
Sichuan JieYao Co., Ltd.

Contact:+86-838-5655598

Address:Guanghan Nanfeng Industrial Zone
Wuhan Chemwish Technology Co., Ltd

website:http://www.chemwish.com/

Contact:+86-27-67849912

Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China
Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

website:http://www.bjgreenchem.com/

Contact:+86-427-6515887

Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
SuZhou Ascepion Pharmaceuticals, Inc.(expird)

Contact:0512-86881668

Address:Building C,68Xingqing Road,Suzhou,China.

Relevant to this article

Tandem radical cyclizations on lodoaryl azides: synthesis of the core tetracycle of aspidosperma alkaloids

Doi:10.1021/jo990891x
(1999)
Cu^I-catalyzed conjugate addition of silyl boronic esters: Retracing catalytic cycles using isolated copper and boron enolate intermediates

Doi:10.1021/om500989w
(2014)
A convenient synthesis of cis-Mo(CO)₄L₂ derivatives (L = group 5A ligand) and a qualitative study of their thermal reactivity toward ligand dissociation

Doi:10.1021/ic50187a062
(1978)
Sulfonate protecting groups. Regioselective O-sulfonylation of myo-inositol orthoesters

Doi:10.1016/S0040-4039(01)00364-1
(2001)
Highly selective synthesis of 2-(2H-1,2,3-Triazol-2-yl)benzoic acids

Doi:10.1021/acs.oprd.8b00349
(2019)
Stereocontolled synthesis of (-)-afzelechin: General route to catechin-class polyphenols by solving an S_N2 vs. S_N1 problem

Doi:10.1246/cl.2009.934
(2009)

Article Doi