Preparation and Pharmacological Evaluation of Enantiomers of Certain Nonoxygenated Aporphines: (+)- and (-)-Aporphine and (+)- and (-)-10-Methylaporphine

DOI: 10.1021/jm00062a002

Source and publish data:

Journal of Medicinal Chemistry p. 1316 - 1318 (1993)

Update date:2022-08-04

Topics: Pharmacological evaluation Enantiomers Preparation

Authors:

Cannon, Joseph G.

Raghupathi, Revathi

Moe, Scott T.

Johnson, Alan K.

Long, John Paul

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Article abstract of DOI:10.1021/jm00062a002

The subject compounds were prepared as a part of a continuing structure-activity study of the contrasting actions (agonism-antagonism) of (+)- and (-)-11-hydroxy-10-methylaporphine at serotonin (5-HT_1A) receptors. None of the targeted nonoxygen

Full text of DOI:10.1021/jm00062a002

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