Facile fluorination of deoxy-4'-thiopyrimidine nucleosides with 'down' hydroxyl group retention of configuration after fluoride opening of the quaternized N3-MEM anhydronucleosides

DOI: 10.1016/S0040-4039(00)78346-8

Source and publish data:

Tetrahedron Letters p. 7573 - 7576 (1994)

Update date:2022-07-30

Topics: Fluorination Retention of configuration

Authors:

Jeong Jeong

Nicklaus

George George

Marquez Marquez

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Article abstract of DOI:10.1016/S0040-4039(00)78346-8

Attempted fluorination of 1-(5-O-trityl-3-deoxy-4-thio-β-D-erythro-pentofuranosyl)-3-(2-methoxy ethoxymethyl)uracil (12) and 1-(5-O-trityl-2-deoxy-4-thio-β-D-erythro-pentofuranosyl)-3-(2-methoxy ethoxymethyl)uracil (14) with diethylaminosulfur trifluoride

Full text of DOI:10.1016/S0040-4039(00)78346-8

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