Synthesis and biological activity of the metabolites of syn-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]non-9-yl 4-Chlorobenzoate hydrochloride

DOI: 10.1248/cpb.42.2365

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2365 - 2369 (1994)

Update date:2022-09-26

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Authors:

Yamawaki

Bukovac Bukovac

Sunami Sunami

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Article abstract of DOI:10.1248/cpb.42.2365

Five metabolites of syn-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]non-9-yl 4-chlorobenzoate hydrochloride (YUTAC) (1) were prepared and examined for Na⁺ current blocking activity in guinea pig ventricular myocytes. These metabolites showed lower

Full text of DOI:10.1248/cpb.42.2365

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