Journal of Medicinal Chemistry p. 2557 - 2569 (1995)
Update date:2022-08-04
Topics:
Michne, William F.
Schroeder, Joseph D.
Guiles, Joseph W.
Treasurywala, Adi M.
Weigelt, Carolyn A.
et al.
The preparation of a series of quinazoline-2,4-diones, 1-3, and pyrrolo<3,4-d>pyrimidine-2,4-diones, 4-8 is described.A small number of quinazolinedione analogs were identified from random screening to possess low micromolar (1.3-4.4 μM) potency in the nu
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