Addition of 2-lithiofuran to chiral α-alkoxy nitrones; a stereoselective approach to α-epimeric β-alkoxy-α-amino acids

Article abstract of DOI:10.1055/s-1994-25712

The addition of 2-lithiofuran (1) to the N-benzyl nitrones 2a-d, derived from chiral α-alkoxy aldehydes, affords β-alkoxy-α-hydroxyamino-2-alkylfurans in good yields and with syn selectivity. Conversely, the reaction with the same nitrones precomplexed wi