Reaction of uridines and thymidines with methyl propynoate. A new N-3 protecting group

DOI: 10.1016/0040-4039(95)00460-T

Source and publish data:

Tetrahedron Letters p. 3261 - 3264 (1995)

Update date:2022-07-29

Topics:

Authors:

Faja, Montserrat

Ariza, Xavier

Galvez, Carmen

Vilarrasa, Jaume

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Article abstract of DOI:10.1016/0040-4039(95)00460-T

A fast conjugated addition takes place when uridines and thymidines are treated with HC≡C-COOMe in the presence of suitable bases such as DMAP. As the resulting N-CH=CH-COOMe moiety appears to be very stable under acidic conditions, but it is readily clea

Full text of DOI:10.1016/0040-4039(95)00460-T

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