
Tetrahedron p. 6591 - 6604 (1995)
Update date:2022-08-04
Topics:
Denholm, Alastair A.
Jennens, Lyn
Ley, Steven V.
Wood, Anthony
A potential relay route for the synthesis of azadirachtin (1) has been established.An advanced intermediate 4 has been prepared and methods to convert this back to the natural product has been developed, in particular, the reintroduction of the enol double bond using an acetal exchange process.
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