Chemical and Pharmaceutical Bulletin p. 1064 - 1066 (1995)
Update date:2022-09-26
Topics:
Muratake
Matsumura
Natsume
A total synthesis of natural (+)-duocarmycin SA (1) was achieved as shown in Chart 1, starting from L-malic acid (5) by using a Lewis acid-mediated indole formation reaction of a pyrrole precursor 14 to form the key compound 15.
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Doi:10.1039/J19700000889
()Doi:10.1139/v67-339
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()Doi:10.1016/0022-1139(94)03201-A
(1995)Doi:10.1080/00397919508011794
(1995)Doi:10.1002/ejoc.201700138
(2017)