Journal of the Chemical Society. Perkin transactions I p. 1273 - 1280 (1995)
Update date:2022-08-02
Topics:
Patrick, Graham L.
Treatment of 5-(2-arylethyl)-1,2,3,4,5,6,7,8-octahydroisoquinolines with 48percent HBr resulted in isomerisation of the double bond and subsequent cyclisation at position 6 of the octahydroisoquinoline ring system to give (+/-)-<4aα,4bβ,10bβ,12aβ>-9-halogeno-2-methyl-1,2,3,4,4a,4b,5,6,10b,11,12,12a-dodecahydronaphtho2,1-f>isoquinolines.The products obtained represent novel analogues of aza-D-homoestranes.No reaction was observed with the corresponding 5,5-disubstituted octahydroisoquinolines.An X-ray crystallographic study of compound 10 (X = Br) is described.
View MoreJinTan Pingsheng Chemical Co.,Ltd
Contact:+86-519-82828200
Address:NO.11Danfengxilu Road,Jintan City,Jiangsu,China
website:https://www.finerchem.com
Contact:+86-531-88989536
Address:New Material Industrial Park, Jinan City, China
Ji'nan Orgachem Pharmaceutical Co.,Ltd
Contact:+86-531-82687810
Address:Jinan
Wuhan Kemi-Works Chemical Co., Ltd
website:http://www.kemiworks.com
Contact:86-27-85736489
Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Guangzhou Flower's Song Fine Chemical CO,. Ltd
Contact:+86-20-87475199
Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
Doi:10.1016/0022-328X(95)05532-T
(1995)Doi:10.1007/BF02256813
(1998)Doi:10.1016/0040-4020(96)00879-4
(1996)Doi:10.1039/J19670001096
()Doi:10.1021/ja01299a027
(1936)Doi:10.1021/acs.orglett.0c02116
(2020)
