Carbon-Carbon Bond Formation with New Mitsunobu Reagents

Article abstract of DOI:10.1016/0040-4039(95)00300-2

The efficiency of three azodicarboxylic acid derivatives and a stabilized phosphorane in the Mitsunobu type C-C bond formation was compared utilizing the reactions of three nucleophiles of different pK_a's and several alcohols of different structure types.The study established the characteristics of each reagent.The synthesis of two insect pheromone analogs was accomplished effectively using these homologation reactions.