A Novel Nucleoside Phosphoramidite Synthon Derived from 1R,2S-Ephedrine

DOI: 10.1016/0957-4166(95)00122-6

Source and publish data:

Tetrahedron Asymmetry p. 1051 - 1054 (1995)

Update date:2022-08-05

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Authors:

Iyer, Radhakrishnan P.

Yu, Dong

Ho, Nan-Hui

Tan, Weitian

Agrawal, Sudhir

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Article abstract of DOI:10.1016/0957-4166(95)00122-6

The stereoselective synthesis of the nucleoside phosphoramidite 6 by reaction of the chiral oxazaphospholidine 4 with 5'-DMT-T is reported.The novel phosphoramidite synthon, 6, is stereoselectively converted to 8 by oxidative sulfurization with 1.The oxaz

Full text of DOI:10.1016/0957-4166(95)00122-6

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Product name:1-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-((2R,4S,5R)-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidin-2-yloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

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