Total synthesis of nagstatin, an n-acetyl-β-glucosaminidase inhibitor

Article abstract of DOI:10.1016/00404-0399(50)1361-K

The first enantiospecific total synthesis of nagstatin has been accomplished through the regioselective introduction of an allyl group on the imidazole ring of the de-branched nagstatin precursor followed by conversion into the carboxymethyl group, and th