Tetrahedron Letters p. 7675 - 7678 (1996)
Update date:2022-07-30
Topics:
Manoharan, Muthiah
Ramasamy, Kanda S.
Mohan, Venkatraman
Cook, P. Dan
A phosphoramidite with an aminopropyl group placed at the N2-position of 2'-deoxyguanosine has been synthesized and incorporated into oligonucleotides. This modification shows enhanced binding properties against both DNA and RNA targets and is useful for conjugating other functionalities.
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