2-Azanorbornane-based amine organocatalyst for enantioselective aldol reaction of isatins with ketones

DOI: 10.1016/j.tetasy.2016.08.013

Source and publish data:

Tetrahedron Asymmetry p. 1062 - 1068 (2016)

Update date:2022-08-03

Topics: NMR spectroscopy Enantioselective Ketones Enantiomeric excess Aldol Reaction Chiral HPLC Isatins Catalyst Screening Yield determination

Authors:

Ogasawara, Ayumi

Subba Reddy

Seki, Chigusa

Okuyama, Yuko

Uwai, Koji

Tokiwa, Michio

Takeshita, Mitsuhiro

Nakano, Hiroto

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Article abstract of DOI:10.1016/j.tetasy.2016.08.013

Optically active 2-azanorbornane-based organocatalysts were designed and synthesized, and the catalytic activity of these catalysts in enantioselective aldol reactions of isatins with ketones was investigated. Among these catalysts, 2-azanorbornylmethanol

Full text of DOI:10.1016/j.tetasy.2016.08.013

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