For more complex mixtures or when traditional separation methods are insufficient, chiral HPLC can be used to separate diastereomers based on their enantiomeric differences.
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(2S,6S,8R)-8-methyl-2-tosyloxymethyl-1,7-dioxaspiro<5.5>undecane
(Z)-methyl 3-(tert-butoxycarbonylamino)-2-methylacrylate
(R)-(4-Chlorophenyl)(pyridin-2-yl)methanol
Propanoic acid, 3-[3-hydroxy-2-(hydroxymethyl)-2-methyl-1-oxopropoxy]-2-[[3-hydroxy-2- (hydroxymethyl)-2-methyl-1-oxopropoxy]methyl]-2-methyl-, phenylmethyl ester
(R)-4,4,5,5-tetramethyl-2-(1-phenylpropyl)-1,3,2-dioxaborolane
(S)-N-benzyl-1-(1-nbutylpyrrolidin-2-yl)methanamine
(2S,4aS,5R,8aR)-N-phenoxycarbonyl-2-propyl-5-methyl-decahydroquinolin-4-one
tert-butyl (5-chloro-2-iodophenyl)carbamate
(4S,4'S,5S,5'S)-2,2'-(4-vinylpyridine-2,6-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole)
1-(4-(benzyloxy)phenyl)hex-5-en-3-ol
2-(2-phenyl-allyloxy)-naphthalene-1-carbaldehyde
(2S,3S)-2-benzyl-3-hydroxy-2-methylcyclohexanone
1-Phenylsulfanyl-naphthalene-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
(1R,2S)-2-acetoxy-1-indanol
(+/-)-3,9-bis(4-methoxyphenyl)spiro<5.5>undecane
1-(4-(tert-butyldimethylsilyloxy)phenyl)-2-chloroethanol
(S,S)-3-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-1,1-dicarbomethoxy-4-methylcyclopentane
(1S,3S,4R)-2-((R)-1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid ethyl ester
