
Tetrahedron Letters p. 5777 - 5780 (1995)
Update date:2022-08-03
Topics:
Kadota, Isao
Jung-Youl, Park
Koumura, Nagatoshi
Pollaud, Guy
Matsukawa, Yasuhisa
Yamamoto, Yoshinori
The total synthesis of Hemibrevetoxin B is described. A new cyclization approach, based on the Lewis acid mediated intramolecular cyclization of the γ-oxo-substituted allylic tin having an aldehyde group, produced the 6-6-7-7 polycyclic ether skeleton of
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Doi:10.1021/jacs.7b12673
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