An efficient synthesis of 3-methyl-3-trifluoromethyl azetidin-2-one

DOI: 10.1016/0022-1139(94)03198-9

Source and publish data:

Journal of Fluorine Chemistry p. 57 - 60 (1995)

Update date:2022-08-05

Topics:

Authors:

Haddad, Mansour

Wakselman, Claude

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0022-1139(94)03198-9

The Curtius rearrangement has been used as a key step for the transformation of the unsaturated ester 1 to the 3-trifluoromethylated 2-azetidinone 7 via a six-step synthesis. - Keywords: Trifluoromethyl: Azetidinone; β-Lactam; Curtius rearrangement; Antibiotics

Full text of DOI:10.1016/0022-1139(94)03198-9

Products guided by the article

Product name:2-Benzyloxycarbonylamino-2-methyl-2-trifluoromethylpropanaldehyde

Cas No:170162-75-1

R&D Labs maybe for 170162-75-1

Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.
Shanghai Maxchemco Chemical Industry Co., Ltd.

Contact:(86)21-51079223

Address:No.1305-8, B241, the Ecust Park, Huajing Road, Xuhui District, Shanghai
Tianjin Bright Future Technology Co., Ltd

Contact:0086-22-58016666

Address:NO.136 DongTeng Lake Street Tianjin Economic and Technology Development Area,Tainjin,China
Hebei yanxi chemical co.,LTD.

website:https://en.yan-xi.com/

Contact:+86 17531190177--

Address:Zhang zhe, guangzong county, xingtai city, hebei province
Sinochem Jiangsu Co.,Ltd.

Contact:86-25-51817806

Address:No. 216, middle longpan road, jincheng tower, floor 21-22, nanjing ,china

Relevant to this article

First Michael addition reaction of α-substituted N-diphenylmethyleneglycinate with ethyl propiolate. Synthesis of α-substituted (E)-3,4-dehydroglutamic acids

Doi:10.1016/00404-0399(50)1149C-
(1995)
Total syntheses and re-assignment of configurations of the cyclopeptides lissoclinamide 4 and lissoclinamide 5 from Lissoclinum patella

Doi:10.1039/a909360e
(2000)
Synthesis and X-Ray Crystal Structure of 8,9-Dimethoxy-4-methyl-3-phenyl-2,3,5,6-tetrahydropyrrolo<2,1-a>isoquinolinium Iodide

Doi:10.1071/CH9951437
(1995)
Homo-N-oligonucleotides (N1/N9-C1′ methylene bridge oligonucleotides): Nucleic acids with left-handed helicity

Doi:10.1021/ja049865t
(2004)
Synthesis and Characterization of the Potential Melt-Castable Explosive 3-(1,2,4-Oxadiazolyl)-5-Nitratomethyl Isoxazole

Doi:10.1002/cplu.202100175
(2021)
Benzo Condensed Crown Ethers Containing 1,8-Naphthyridine or 4-Pyridone Units - Synthesis and Complex Formation with Organic Guest Molecules

Doi:10.1002/prac.19953370198
(1995)

Article Doi