An efficient protocol for the preparation of primary alcohols bearing a β-chiral center via an oxazolidinone auxiliary mediated resolution, and application to the synthesis of 4,4-disubstituted piperidine substance P antagonists

DOI: 10.1021/jo9918246

Source and publish data:

Journal of Organic Chemistry p. 2615 - 2618 (2000)

Update date:2022-08-04

Topics:

Authors:

Lewis, Richard T.

Ladduwahetty, Tamara

Merchant, Kevin J.

Keown, Linda E.

Hitzel, Laure

Verrier, Hugh

Stevenson, Graeme I.

MacLeod, Angus M.