A Novel Asymmetric Synthesis of Axial-Equatorial Furofuran Lignans: A Synthesis of (+)-Fargesin

DOI: 10.1016/0040-4039(95)01507-E

Source and publish data:

Tetrahedron Letters p. 7271 - 7274 (1995)

Update date:2022-09-26

Topics:

Authors:

Yoshida, Shin-ichi

Yamanaka, Takeshi

Miyake, Tutomu

Moritani, Yasunori

Ohmizu, Hiroshi

Iwasaki, Tameo

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Article abstract of DOI:10.1016/0040-4039(95)01507-E

(+)-Fargesin (6), a representative example of the axial-equatorial furofuran lignans having two different aryl groups, was efficiently synthesized based on a highly diastereoselective Michael addition reaction of the cyanohydrin 1 to methyl (S)-3-(2,2-dim

Full text of DOI:10.1016/0040-4039(95)01507-E

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Product name:(3S,4S,5R)-4-((S)-Benzo[1,3]dioxol-5-yl-hydroxy-methyl)-3-[(R)-(3,4-dimethoxy-phenyl)-hydroxy-methyl]-5-methoxy-dihydro-furan-2-one

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