Tetrahedron p. 9699 - 9712 (1995)
Update date:2022-08-03
Topics:
Aar, Marcel P. M. van
Thijs, Lambertus
Zwanenburg, Binne
A general stereoselective synthesis of 4,5-dihydroxy-2-alkene esters is developed using the photo-induced rearrangement of α,β-epoxy diazomethyl ketones.Starting with readily available enantiopure allylic alcohols that contain a chiral center at C4, i.e. a protected secondary alcohol function, a neighboring stereogenic center is introduced by irradiation of the mentioned diazo ketones.The configuration of this newly introduced center is determined by the chiral inductor used in the Sharpless epoxidation of the allylic alcohol and therefore can be selected at will.
View MoreShanghai Dano Pharmaceutical Co.,Ld.(expird)
Contact:+86-592-6266840
Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
Landz International Company Ltd.
Contact:0086-21-58891610
Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Shanghai Pengkai Chemical Co.,Ltd
Contact:+86-21-60526671
Address:No.4226 Duzhuang Rd Minhang District Shanghai China
Changzhou Hopschain Chemical Co.,Ltd
website:http://www.hopschem.cn/products.html
Contact:86-519-85528066
Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Chengdu Pukang Biotechnology Co., Ltd
website:http://www.pu-kang.com
Contact:86-028-63976226
Address:No. 868 Xiwang Road,Xinjin county,Chengdu city, China
Doi:10.1016/0277-5387(95)00083-5
(1996)Doi:10.1246/bcsj.68.2757
(1995)Doi:10.1055/s-2004-831234
(2004)Doi:10.1021/jo00125a050
(1995)Doi:10.1021/ja312194k
(2013)Doi:10.1039/DT9950003007
(1995)