Tetrahedron p. 9699 - 9712 (1995)
Update date:2022-08-03
Topics:
Aar, Marcel P. M. van
Thijs, Lambertus
Zwanenburg, Binne
A general stereoselective synthesis of 4,5-dihydroxy-2-alkene esters is developed using the photo-induced rearrangement of α,β-epoxy diazomethyl ketones.Starting with readily available enantiopure allylic alcohols that contain a chiral center at C4, i.e. a protected secondary alcohol function, a neighboring stereogenic center is introduced by irradiation of the mentioned diazo ketones.The configuration of this newly introduced center is determined by the chiral inductor used in the Sharpless epoxidation of the allylic alcohol and therefore can be selected at will.
View MoreContact:+1-973-357-0577
Address:10 Taft Rd.
Contact:0086-29-89196322
Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
Chongqing maohuan Chemicals Co., Ltd
website:http://www.bschem.com
Contact:+86 13996103726
Address:Chongqing Nan'an District Tu Town
Huangshan Honghui Pharm Technology Co., Ltd.(expird)
website:http://www.honghuichem.com
Contact:18855958372
Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
website:http://www.maisonchem.com.cn
Contact:0086-311-83833777
Address:Leitou industrial district, xinji, shijiazhuang city, hebei province,
Doi:10.1016/0277-5387(95)00083-5
(1996)Doi:10.1246/bcsj.68.2757
(1995)Doi:10.1055/s-2004-831234
(2004)Doi:10.1021/jo00125a050
(1995)Doi:10.1021/ja312194k
(2013)Doi:10.1039/DT9950003007
(1995)