Enantiospecific synthesis of heterocyclic compounds: An approach to functionalised tetrahydrofurans from intramolecular dipolar cycloadditions

DOI: 10.1016/0040-4039(95)01575-3

Source and publish data:

Tetrahedron Letters p. 7731 - 7734 (1995)

Update date:2022-07-29

Topics:

Authors:

Hewson, Alan T.

Jeffery, Jim

Szczur, Natalka

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Article abstract of DOI:10.1016/0040-4039(95)01575-3

Intramolecular cycloaddition of the nitrone 8, derived from the glucal 1, produces stereospecifically the isoxazolidins 9, which may be reductively cleaved to afford functionalised aminotetrahydrofuran polyols such as 20 and 23.

Full text of DOI:10.1016/0040-4039(95)01575-3

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