(2R,3S)- and (2S,3R)-2-benzyl-3,4-epoxybutanoic acid as highly efficient and fast acting pseudomechanism-based inactivators for carboxypeptidase A: design, asymmetric synthesis and inhibitory kinetics

DOI: 10.1039/P19950002877

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2877 - 2882 (1995)

Update date:2022-08-05

Topics:

Authors:

Lee, Soo Suk

Li, Zhi-Hong

Lee, Dong Ha

Kim, Dong H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P19950002877

2-benzyl-3,4-epoxybutanoic acid (BEBA) was studied as an irreversible inhibitor for the zinc-containing protease, carboxypeptidase A.Of four possible stereoisomers, those having a 2R,3S- and a 2S,3R- configuration inhibited carboxypeptidase A in a time-de

Full text of DOI:10.1039/P19950002877

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:dibenzyl (2S,3R)-2-benzyl-3-hydroxysuccinate

Cas No:172101-55-2

R&D Labs maybe for 172101-55-2

Zhangjiagang Jianing Import & Export Co.,Ltd.

Contact:086-512-55379012 13913607595

Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Shanghai united Scientific Co.,Ltd.

Contact:+86-21-53535353

Address:28F No.900 huaihai Road Shanghai China
shijiazhuang baisheng chem co.; ltd

Contact:86-0311-80790826

Address:shijiazhuang hebei
NINGBO YINLIANG FOREIGN TRADE CO., LTD.

Contact:+86-574-87834016 / 87898057

Address:23F NO.666JINYU ROAD,YINGZHOU DISTRICT,NINGBO.CHINA
JIN TAN CHENG'EN CHEMICAL CO.,LTD.

Contact:86-519-82116250

Address:NO.102，village Dongfang，conomic development zone

Relevant to this article

Generation of Phosphoranyl Radicals via Photoredox Catalysis Enables Voltage-Independent Activation of Strong C-O Bonds

Doi:10.1021/acscatal.8b03592
(2018)
Synthese von modifizierten Tetrasacchariden als analoge Akzeptor-Inhibitoren der N-Acetylglucosaminyltransferase II

Doi:10.1016/0008-6215(95)00056-Y
(1995)
Platinum(II) complexes with dithiolates and phosphinites as ligands: Crystal structure of [Pt{S₂CO}{P(OMe)Ph₂}₂]

Doi:10.1016/0277-5387(95)00261-P
(1996)
Efficient synthesis of α- and δ-carbolines by sequential Pd-catalyzed site-selective C-C and twofold C-N coupling reactions

Doi:10.1039/c4ob02226b
(2015)
SYNTHESIS AND BIOLOGICAL PROPERTIES OF N-SUBSTITUTED &α,&β-DEHYDRODIPEPTIDES

Doi:10.1007/BF02219068
(1995)
Ligand- and catalyst-free intramolecular C-S bond formation: Direct access to indalothiochromen- 4-ones

Doi:10.1515/hc-2014-0206
(2015)

Article Doi