A formal total synthesis of nikkomycin B based on enzymatic resolution of a primary alcohol possessing two stereogenic centers

DOI: 10.1016/0957-4166(95)00282-T

Source and publish data:

Tetrahedron Asymmetry p. 2131 - 2134 (1995)

Update date:2022-09-26

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Authors:

Akita Akita

Chen Chen

Uchida Uchida

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Article abstract of DOI:10.1016/0957-4166(95)00282-T

A highly stereoselective synthesis of the versatile chiral synthon possessing two stereogenic centers, (2S,3S)-8 (>99% ee) was achieved and the conversion of (2S,3S)-8 into the homochiral intermediate (2S,3S,4S)-1 for the synthesis of nikkomycin B is described.

Full text of DOI:10.1016/0957-4166(95)00282-T

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