An enantioselective route to cis- and trans-2-(hydroxymethyl)-5-alkylpyrrolidines

DOI: 10.1021/jo00124a021

Source and publish data:

Journal of Organic Chemistry p. 6091 - 6096 (1995)

Update date:2022-08-02

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Authors:

Pettersson-Fasth

Riesinger

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Article abstract of DOI:10.1021/jo00124a021

A general method for the enantioselective preparation of 2,5-disubstituted pyrrolidines has been developed. A variety of cis- and trans-2-(hydroxymethyl)-5-alkylpyrrolidines were synthesized using 1-(benzyloxy)-5-(p-toluenesulfonamido)-3-alken-2-ols as common intermediates.

Full text of DOI:10.1021/jo00124a021

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