Ring opening and ring closure reactions of 1,2,4-triazines with carbon nucleophiles: A novel route to functionalized 3-aminopyridazines

Article abstract of DOI:10.1016/0040-4039(96)01228-2

A novel route to functionalized 3-aminopyridazines by reaction of 6-substituted 3-chloro-1,2,4-triazines with carbon nucleophiles bearing a cyano substituent at a carbanionic center was developed and a key part of the reaction mechanism was elucidated bas