Asymmetric synthesis of 1-aryl-1,2,3,4-tetrahydroisoquinolines part 1: Addition of chiral phenylacetaldehyde acetals to acylimines

DOI: 10.1016/0040-4039(95)01716-U

Source and publish data:

Tetrahedron Letters p. 8003 - 8006 (1995)

Update date:2022-08-05

Topics:

Authors:

Wuensch, Bernhard

Nerdinger, Sven

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01716-U

The stereoselectivity in the addition of the enantiomerically pure (2-bromophenyl)acetaldehyde acetals 3a-g to the acylimines 4a,b is investigated. Based on this reaction a novel asymmetric synthesis for the 1-phenyl-tetrahydroisoquinoline 8 is elaborated.

Full text of DOI:10.1016/0040-4039(95)01716-U

Products guided by the article

Product name:(4R,5R)-2-(2-Bromo-benzyl)-4,5-bis-(1-methoxy-1-methyl-ethyl)-[1,3]dioxolane

Cas No:172794-67-1

R&D Labs maybe for 172794-67-1

Angel Yeast Co., Ltd.

Contact:+86-717-6370352

Address:168 Chengdong Avenue, Yichang, Hubei 443003, P. R.China
Shandong Yubin Chemical CO.,LTD

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
ANTAI BIO-TECH CO LTD

website:http://www.antaibio.com

Contact:0086-21-65663057

Address:Room 2108, Building 2，No. 489 Zhengli Road，200433
Shanghai Norky Pharmaceutical Co., LTD.

website:http://www.norkypharm.com

Contact:86-21-61075300

Address:1165 Jiangning Road, Office 1502, Shanghai, China
Shanghai Yuking Water Soluble Material Tech Co., Ltd

Contact:86-21-68286299

Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China

Relevant to this article

Chiral synthesis of 4-[1-(2-deoxy-β-L-ribofuranosyl)] derivatives of 2-substituted 5-fluoroaniline: "Cytosine replacement" analogues of deoxy-β-L-cytidine

Doi:10.1021/jo000510b
(2000)
Mono-, di- and tri-antennary D-galactose ligands as competitive inhibitors and photoaffinity labels of the hexose transporting system in erythrocytes. A model for the irreversible blocking of receptors in cell membranes

Doi:10.1016/0008-6215(95)00145-J
(1995)
Isothiazoles. Part V. Cycloaddition reaction of nitrile oxides to 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide: An entry to 5-acyl- and 5-cyano-isothiazole 1,1-dioxide derivatives

Doi:10.1016/0040-4020(95)00779-8
(1995)
Doi:10.1021/jo01257a044
(1969)
Synthesis of aryl trimethylstannanes from aryl halides: An efficient photochemical method

Doi:10.1039/c6cc01135g
(2016)
An efficient procedure for palladium-catalyzed reduction of aryl/enol triflates

Doi:10.1055/s-1995-4120
(1995)

Article Doi