Isothiazoles. Part V. Cycloaddition reaction of nitrile oxides to 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide: An entry to 5-acyl- and 5-cyano-isothiazole 1,1-dioxide derivatives

DOI: 10.1016/0040-4020(95)00779-8

Source and publish data:

Tetrahedron p. 12351 - 12362 (1995)

Update date:2022-08-05

Topics:

Authors:

Clerici Clerici

Ferraris

Gelmi Gelmi

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Article abstract of DOI:10.1016/0040-4020(95)00779-8

Nitrile oxides 2 reacted with 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide (1) affording through a highly regioselective 1,3-dipolar cycloaddition reaction isothiazolo[5,4-d]isoxazoline 4,4-dioxides 3. Reduction of 3 afforded a mixture of th

Full text of DOI:10.1016/0040-4020(95)00779-8

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