The first synthesis of N-alkyl-N-arylthiocarbamoylacetates and acetic acids

Article abstract of DOI:10.1080/00397910008087354

N-Alkyl-N-arylthiocarbamoylacetates, the key intermediates for the synthesis of novel antinephritic agents, have been prepared for the first time. Some of the esters were in turn hydrolyzed to the corresponding acids. An alternative, indirect synthetic route was also developed to prepare some unusual acids.

Full text of DOI:10.1080/00397910008087354

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Synthetic Communications: An
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Organic Chemistry
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The First Synthesis of N-Alkyl-
N-Arylthiocarbamoylacetates
and Acetic Acids
Glen W. Spears a , Kiyoshi Tsuji a , Takashi Tojo a ,
Hiroaki Nishimura a & Takashi Ogino a
a Medicinal Chemistry Research Laboratories,
Fujisawa Pharmaceutical Co., Ltd. , 1--6, Kashima 2-
chome, Yodogawa-ku, Osaka, 532--8514, Japan
Published online: 04 Dec 2007.
To cite this article: Glen W. Spears , Kiyoshi Tsuji , Takashi Tojo , Hiroaki Nishimura
& Takashi Ogino (2000) The First Synthesis of N-Alkyl-N-Arylthiocarbamoylacetates
and Acetic Acids, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 30:3, 565-574, DOI:
10.1080/00397910008087354
To link to this article: http://dx.doi.org/10.1080/00397910008087354
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