Tetrahedron Asymmetry p. 2977 - 2990 (1995)
Update date:2022-07-30
Topics:
Vidari
Lanfranchi
Sartori
Serra
The enantioselective synthesis of the right-hand lactone moiety 5 of saponaceolide B, 2, is described. The mean graph profiles of 5 do not match the characteristic patterns of differential cytotoxicity of saponaceolides A, 1, and B, 2, in the NC1 human disease-oriented tumor screening panel, pointing out the need of the entire saponaceolide structure for maintaining the specificity and potency of the antitumor activity. En route to 5 several useful chiral building blocks, such as compounds 6, 10, 19, 27, and 28 were prepared.
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Doi:10.1016/S0968-0896(00)00235-2
(2001)Doi:10.1246/bcsj.75.855
(2002)Doi:10.1021/jo9807417
(1998)Doi:10.1039/c39950002261
(1995)Doi:10.1016/0040-4039(95)01828-6
(1995)Doi:10.1007/s11094-016-1354-9
(2016)