A,3-Allylic Strain as a Control Element in the Paterno-Buechi Reaction of Chiral Silyl Enol Ethers: Synthesis of Diastereomerically Pure Oxetanes Containing Four Contiguous Stereogenic Centers

Article abstract of DOI:10.1021/ja963827v

The facial diastereoselectivity in the Paterno-Buechi reaction of chiral enol ethers and benzaldehyde was studied. The substituents (R^S, R^L) at the stereogenic carbon atom (-C*HR^SR^L) attached to the β-position o