Synthesis of a Chiral Di(hydroxyalkyl) Substituted Bicyclic Guanidine

DOI: 10.1016/0957-4166(95)00354-R

Source and publish data:

Tetrahedron Asymmetry p. 2673 - 2674 (1995)

Update date:2022-08-03

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Authors:

Muenster, Ingo

Rolle, Ulrike

Madder, Annemieke

Clerq, Pierre J. De

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Article abstract of DOI:10.1016/0957-4166(95)00354-R

Schmidtchen's methodology is used successfully for the synthesis of the chiral disubstituted bicyclic guanidinium salt 2.The two therefore required primary amine compounds 6 and 9 are obtained from L-methionine and L-glutamic acid, respectively.

Full text of DOI:10.1016/0957-4166(95)00354-R

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