Generation and subsequent cycloaddition chemistry of α-amino isobenzofurans formed by cationic cyclization

Article abstract of DOI:10.1016/0040-4039(95)02013-F

The α-thiocarbocation generated from the Pummerer reaction of an o-amido substituted sulfoxide is intercepted by the adjacent carbonyl group to produce an α-amino isobenzofuran as a transient intermediate which undergoes a subsequent Diels-Alder cycloaddi