Synthesis of 8-oxo-7,8-dihydro-6-O-methyl-2′-deoxyguanosine and its use as a probe to study DNA-base excision by mutY enzyme

DOI: 10.1016/0040-4039(95)02069-1

Source and publish data:

Tetrahedron Letters p. 9 - 12 (1996)

Update date:2022-08-03

Topics:

Authors:

Varaprasad, Chamakura V.

Bulychev, Nickolai

Grollman, Arthur P.

Johnson, Francis

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)02069-1

A 23mer oligomer containing 8-oxo-7,8-dihydro-6-O-methyl-2′-deoxyguanosine (1) has been synthesized from 2′-deoxyguanosine. The activity of MutY protein toward this and a related oligomer containing 8-methoxy-dG has been studied.

Full text of DOI:10.1016/0040-4039(95)02069-1

Products guided by the article

Product name:2-Amino-8-benzyloxy-9-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1,9-dihydro-purin-6-one

Cas No:174361-94-5

R&D Labs maybe for 174361-94-5

Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China
Zhangjiagang Jianing Import & Export Co.,Ltd.

Contact:086-512-55379012 13913607595

Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-39971718

Address:859 jiadingchengliu shanghai
Changzhou Kingyo Chemical Corporation Ltd.

website:http://www.kingyochem.com

Contact:+86-519-85105717

Address:19# Wuqing North Road, Changzhou , Jiangsu, China

Relevant to this article

Doi:10.1016/0040-4020(68)88136-0
(1968)
Stereospecific synthesis of tetradeuterated (R)- and (S)-ifosfamide

Doi:10.1002/(SICI)1099-1344(199602)38:2<105::AID-JLCR821>3.0.CO;2-X
(1996)
Synthetic studies of halichondrin B, an antitumor polyether macrolide isolated from a marine sponge. 7. Synthesis of two C27-C36 units via construction of the F ring and completely stereoselective C-glycosylation using mixed Lewis acids

Doi:10.1248/cpb.45.1558
(1997)
Rhenium(VII) monoimido alkylidyne complexes. The importance of face selectivity in the metathesis of acetylenes via rhenacyclobutadiene intermediates

Doi:10.1021/ja00001a021
(1991)
Identification of neuropeptide s antagonists: Structure-Activity relationship studies, x-ray crystallography, and in vivo evaluation

Doi:10.1021/cn500113c
(2014)
Synthesis of rapamycin-peptide hybrid molecule (RAP-P): High affinity FKBP12 ligand

Doi:10.1016/S0040-4020(96)00068-3
(1996)

Article Doi