Asymmetric reduction of 2-(N-arylimino)-3,3,3-trifluoropropanoic acid esters leading to enantiomerically enriched 3,3,3-trifluoroalanine

DOI: 10.1016/0040-4020(95)00866-7

Source and publish data:

Tetrahedron p. 233 - 244 (1996)

Update date:2022-08-03

Topics:

Authors:

Sakai, Takashi

Yan, Fengyang

Kashino, Setsuo

Uneyama, Kenji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00866-7

Enantiomerically enriched 3,3,3-trifluoroalanine (1) (up to 62 % ee) has been synthesized by the asymmetric reduction of 2-(N-arylimino)-3,3,3-trifluoropropanoic acid esters with a chiral oxazaborolidne catalyst and subsequent oxidative removal of N-aroma

Full text of DOI:10.1016/0040-4020(95)00866-7

Products guided by the article

Product name:N-(benzyloxy)-2,2,2-trifluoroacetamide

Cas No:174075-91-3

R&D Labs maybe for 174075-91-3

JiangXi Hong Run Chemical Co., Ltd

Contact:+86-0791-88521351

Address:XingHuo industrial zone in YongXiu county
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD

Contact:+86-570-6040289

Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
Shandong LuZhou Amino Acid Co., Ltd

Contact:86-539-2218025

Address:yishui economic and technical development zone zhenxing south road
SHANGHAI GILEADER ADVANCE MATERIAL TECHNOLOGY CO.,LTD

website:http://www.tanguitech.com/contact.asp

Contact:+86-021-58692556

Address:No.6 Building,No. 668 Hengan RD Pudong,Shanghai

Relevant to this article

re- and si-face-selective nitroaldol reactions catalyzed by a rigid chiral quaternary ammonium salt: A highly stereoselective synthesis of the HIV protease inhibitor amprenavir (Vertex 478)

Doi:10.1002/(SICI)1521-3773(19990712)38:13/14<1931::AID-ANIE1931>3.0.CO;2-4
(1999)
Chiral dienamides - Substrates for asymmetric synthesis of amido cyclohexenes

Doi:10.1016/0040-4039(95)02040-3
(1995)
Electrophilic phosphonium cations catalyze hydroarylation and hydrothiolation of olefins

Doi:10.1039/c5cc03572d
(2015)
A new efficient method in nucleoside synthesis

Doi:10.1016/0040-4039(96)01929-6
(1996)
Change of mechanical activity to contraction from the relaxation induced by the intracellular Ca²⁺ antagonist KT-362; effects of alkylation of side chain, and substitution of 2,3,4,5-tetrahydro-1,5- benzothiazepine derivatives

Doi:10.1248/cpb.45.1761
(1997)
Lifetime, reduction potential and base-induced fragmentation of the veratryl alcohol radical cation in aqueous solution. Pulse radiolysis studies on a ligninase "Mediator"

Doi:10.1021/jp9812482
(1998)

Article Doi