Asymmetric reduction of 2-(N-arylimino)-3,3,3-trifluoropropanoic acid esters leading to enantiomerically enriched 3,3,3-trifluoroalanine

DOI: 10.1016/0040-4020(95)00866-7

Source and publish data:

Tetrahedron p. 233 - 244 (1996)

Update date:2022-08-03

Topics:

Authors:

Sakai, Takashi

Yan, Fengyang

Kashino, Setsuo

Uneyama, Kenji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00866-7

Enantiomerically enriched 3,3,3-trifluoroalanine (1) (up to 62 % ee) has been synthesized by the asymmetric reduction of 2-(N-arylimino)-3,3,3-trifluoropropanoic acid esters with a chiral oxazaborolidne catalyst and subsequent oxidative removal of N-aroma

Full text of DOI:10.1016/0040-4020(95)00866-7

Products guided by the article

Product name:N-(benzyloxy)-2,2,2-trifluoroacetamide

Cas No:174075-91-3

R&D Labs maybe for 174075-91-3

Zipont chem(wuhan）Tech co.，Ltd

Contact:+86-27-87587198

Address:wuhan
ShiJiaZhuang Dowell Chemical Co.,Ltd.

website:http://www.dowechem.com

Contact:+86-13463963265

Address:Xiyangling village, high tech Zone, Shijiazhuang，Hebei, China
Zhejiang Chemicals Import & Export Corporation

Contact:86-571-87043088

Address:No.37,Qingchun Road,Hangzhou,China
Eastar Chemical Corporation

website:http://www.eastarchem.com/

Contact:1-800-898-2436

Address:1215 K Street, STE 1700
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.

Relevant to this article

re- and si-face-selective nitroaldol reactions catalyzed by a rigid chiral quaternary ammonium salt: A highly stereoselective synthesis of the HIV protease inhibitor amprenavir (Vertex 478)

Doi:10.1002/(SICI)1521-3773(19990712)38:13/14<1931::AID-ANIE1931>3.0.CO;2-4
(1999)
Chiral dienamides - Substrates for asymmetric synthesis of amido cyclohexenes

Doi:10.1016/0040-4039(95)02040-3
(1995)
Electrophilic phosphonium cations catalyze hydroarylation and hydrothiolation of olefins

Doi:10.1039/c5cc03572d
(2015)
A new efficient method in nucleoside synthesis

Doi:10.1016/0040-4039(96)01929-6
(1996)
Change of mechanical activity to contraction from the relaxation induced by the intracellular Ca²⁺ antagonist KT-362; effects of alkylation of side chain, and substitution of 2,3,4,5-tetrahydro-1,5- benzothiazepine derivatives

Doi:10.1248/cpb.45.1761
(1997)
Lifetime, reduction potential and base-induced fragmentation of the veratryl alcohol radical cation in aqueous solution. Pulse radiolysis studies on a ligninase "Mediator"

Doi:10.1021/jp9812482
(1998)

Article Doi