Oligonucleotides containing 7- Or 8-methyl-7-deazaguanine: Steric requirements of major groove substituents on the DNA structure

DOI: 10.1039/cc9960002263

Source and publish data:

Chemical Communications p. 2263 - 2264 (1996)

Update date:2022-07-29

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Authors:

Seela, Frank

Chen, Yaoming

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Article abstract of DOI:10.1039/cc9960002263

Methyl groups in alternating octanucleotides containing 7-methyl-7-deazaguanine and cytosine have steric freedom and maintain the B-DNA structure, whereas the isomeric 8-methyl-7-deazaguanine causes a B-Z transition.

Full text of DOI:10.1039/cc9960002263

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